Loot are the items you obtain through doing various missions or mastering a mission tier. The loot from the level mastery are usually much stronger and less common than the rest of the game's items. Some loot is required in order to do other missions. For example, doing the mission "Take a Hooker Behind the Dumpster," you can get Penis Warts as a random loot drop. A more uncommon loot drop from mastering the Gold level is "Impregnated Bitch Whore," which is required in order to take on the mission "Hooker Brain Abortion."